Table 1. Patient characteristics.
| Patient | Age and Gender | Tumor type1 | # FailedTherapies before AXL1717 | MGMT promoter(methylationStatus) | IDH 1/2(wild-type/mutated) | PTEN(wild-type/deleted) | EGFR(amplified/mutated) |
|---|---|---|---|---|---|---|---|
| 1 | 57 F | GBM | 1 | + | Wild-type | Deleted | vIII mutated |
| 2 | 59 M | GBM | 2 | + | Wild-type | Deleted | Not amplified |
| 3 | 58 F | GBM | 2 | NT2 | NT2 | Deleted | Amplified |
| 4 | 57 M | AA → GBM | 2 | - | Wild-type | Deleted | NT2 |
| 5 | 69 M | GBM | 1 | + | Wild-type | Deleted | Not amplified |
| 6 | 37 M | GBM | 1 | + | Wild-type | Deleted | Not amplified |
| 7 | 61 F | GBM | 1 | - | Wild-type | Wild-type | Not amplified |
| 8 | 53 M | GSC | 3 | + | Wild-type | Wild-type | Not amplified |
| 9 | 59 M | GBM | 3 | + | Wild-type | Wild-type | Not amplified |
1GBM = Glioblastoma; AA = Anaplastic astrocytoma; GSC = Gliosarcoma.
2NT = Not tested.