Table 4. Adverse events (AE/SAE) by patient.

Patient	AE/SAE and grade
1	Grade 4 anemia, neutropenia and thrombocytopenia. Did not recover ≤ Grade 2 in 2 weeks, off study
2	None
3	Grade 4 neutropenia and thrombocytopenia at 400 mg bid; Grade 5 sepsis
4	Grade 3 neutropenia at 300 mg bid
5	Grade 3 neutropenia at 300 mg bid; none at 215 mg bid
6	Grade 1 paresthesias
7	None
8	Grade 3 neutropenia at 300 mg bid; Grade 2 at 215 mg bid, off study
9	None