Table 4. miTranscriptome-defined LUAD lineage-specific lncRNAs.
miTranscriptome | Alternate IDs | Position (GRCh37/hg19) | Genomic Context | Patient Outcome |
---|---|---|---|---|
CAT1100.3 | PVT1 | chr8:128996355-129130070 (−) | Adjacent to MYC oncogene | Correlated to MYC expression and tumor progression. PVT1 presence indicates poorer prognosis for patients |
DPYD-AS1.2 | NR_046590.1 | chr1:97720954-97751573 (+) | Antisense to DYPD | DYPD implicated in increased toxicity to patients treated with 5FU. |
LACAT24 | LOC101927132 | chr16:47936832-47961855 (+) | Intergenic | Unknown |
LACAT8.1 | LACAT8 | chr12:131471968-131478539 (−) | Antisense to GPR133 (ADGRD1) | GPR133 upregulation correlated to poorer survival in GBM |
miTranscriptome-calcuated lncRNAs with lineage specificity to LUAD.