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. 2017 Jul 12;8(46):81572–81582. doi: 10.18632/oncotarget.19197

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Copyright: © 2017 Hao et al.

This article is distributed under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.

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(A) lncRNA BC032469 functions as a ceRNA to sponge for miR-1207-5p, promoting hTERT expression to induce gastric cancer cell proliferation and metastasis. (B) FOXM1 induced lncRNA PVT1 expression at the transcriptional level. Then PVT1 binds to FOXM1 protein to increase its stabilization, forming a positive feedback loop and promoting gastric cancer cell proliferation and metastasis.