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. 2017 Jul 12;8(46):81572–81582. doi: 10.18632/oncotarget.19197

Table 1. The ectopic expression of miRNA in gastric cancer.

miRNA Relative expression Target mRNA Cell biology Clinicopathologic feature Reference
miR-17-5p/20a Up TP53INP1 Cell proliferation and apoptosis Tumor size Wang et al. [25]
miR-100 Down ZBTB7A tumor growth, invasion and metastasis lymphatic metastasis Shi et al. [26]
miR-125b Up PPP1CA cellular proliferation, migration, and invasion tumor size and depth of invasion, lymph nodes, distant metastasis, TNM stage and poor prognosis. Wu et al. [27]
miR-133b Down PTBP1 Tumor growth No association with the clinicopathological future Sugiyama et al. [28]
miR-145 down Ets1 migration, invasion, and angiogenesis tumor invasion and metastasis Zheng et al. [29]
miR-148a Down ROCK1 Migration and invasion TNM stage and lymph node-metastasis Zheng et al. [30]
miR-196a/-196b Up radixin cell migration and invasion TNM stage, lymph node metastasis, poor prognosis Tsai et al. [31]
miR-199a-5p Up klotho cell migration and invasion Tumor size, TNM stage and lymph node metastasis He et al. [32]
miR-302 Down IL-8 Migration and invasion metastasis and prognosis Chen et al. [33]
miR-506 Down ETS1 Angiogenesis and EMT Poor prognosis Li et al. [34]
miR-940 Up ZNF24 Migration and invasion poor prognosis Liu et al. [35]
miR-1182 Down hTERT cell proliferation, migration and invasion Tumor size, differentiation, metastasis, TNM Stage and poor prognosis Zhang et al. [20]
miR-1207-5p/miR-1266 Down hTERT cell proliferation, migration and invasion Tumor size, differentiation, metastasis, TNM Stage and poor prognosis Chen et al. [19]
miR-29a/c Down VEGF vascular cell growth, metastasis, and tube formation - Zhang et al. [36]
miR-29b/c Down DNMT3A Migration and invasion Invasion Cui et al. [37]