| Hypericin |
MCF-7 as well as in MDA-MB-231 cells |
Activation of caspase 3/7 and apoptosis |
Human breast adenocarcinoma |
Kimáková P, Solár P, Fecková B, et al. [109]. |
2017 |
| Photofrin |
Human ESCC cellline SHEEC and parental normal cellline SHEE, primary culture cells |
Controlling for vascular factors |
Esophageal cancer |
Gao S, Liang S, Ding K, et al. [106]. |
2016 |
| Photofrin |
ASTC-a-1 cells |
Bcl-2-interacting mediator of cell death |
Lung adenocarcinoma |
Wang X, He X, Hu S, et al. [107]. |
2015 |
| HMME |
Human tongue squamous cell carcinoma Tca8113 cells in vitro
|
Activation of caspase-3 and apoptosis |
Human tongue squamous carcinoma |
Lai X, Ning F, Xia X, et al. [108]. |
2015 |
| 5- ALA |
Human urothelial cancer cells and human umbilical vein endothelial cells, in vivo PDT with a tumor-bearing animal model |
The ALA-PDT decreased levels of mitochondrial membrane potential and induced cell death mainly via apoptosis in these cells. |
Human urothelial cancer |
Inoue K, Fukuhara H, Kurabayashi A, et al. [56]. |
2013 |
| HPPH |
16 adult patients (median age, 65 years) with biopsy-proved primary or recurrent resectable head and neck squamous cell carcinoma |
— |
Head and neck squamous cell carcinoma |
Rigual NR, Shafirstein G, Frustino J, et al. [59]. |
2013 |
