Table 9. Clinical trials with cell cycle checkpoint inhibitors in HNSCC.
Class | Compound | Combination | Phase | State | NCT number |
---|---|---|---|---|---|
CHK1/2 inhibitor | LY2606368 | / | 1 | Completed | NCT01115790 |
Cisplatin, RT, Cetuximab | 1 | Recruiting | NCT02555644 | ||
WEE1 inhibitor | AZD1775 | Cisplatin, RT | 1 | Recruiting | NCT02585973 |
Cisplatin, RT | 1 | Not yet recruiting | NCT03028766 | ||
Cisplatin, Docetaxel, Surgery | 1 | Recruiting | NCT02508246 | ||
Cisplatin | 2 | Terminated | NCT02196168 |
RT: Radiotherapy, NCT: Number clinicaltrials.gov identifier.