miR-494 |
IGF2BP1 |
Promotes angiogenesis and decreases cellular proliferation |
[8, 9] |
Let-7 |
RAS, CDC25A, CDK6, cyclin D, LIN28, MYC, HMGA2, HOXA9, TGFBR1, BCL-XL, MAP4K3 |
Represses cell proliferation and regulates the cell cycle |
[4, 13] |
miR-155 |
hexokinase 2, APAf-1 |
Promotes glucose metabolism, modulates cellular apoptosis and DNA damage response |
[10, 14] |
miR-153 |
ADAM19, AKT |
Inhibits the migration and invasion of human non-small cell lung cancer, inhibits proliferation and migration, and promotes the apoptosis of cultured lung cancer cells |
[11, 12] |
miR-101 |
COX-2, Lin28B, EZH2 |
Inhibits cell proliferation, inflammation, and dysregulation of the cell cycle |
[15–18] |
miR-135b |
IL-1R1 |
Mediates the inflammatory response |
[19] |
miR-200 |
ZEB, E-cadherin, vimentin |
Promotes EMT |
[20, 21] |
miR-218 |
Slug/ZEB2, tumor protein D52 |
Inhibits cell migration, invasion and EMT |
[22, 23] |
miR-487b |
SUZ12, BMI1, WNT5A, MYC, KRAS |
Represses the proliferation and invasion of LC cells |
[24] |