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. 2017 Jun 9;13(3):63–70. doi: 10.1080/15476278.2017.1329789

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Figure 1. — A model of SCI repair. NeuroRegen scaffold modified with CBD–EGFR-Fab promotes neuronal differentiation of neural stem cells (NSCs) for spinal cord injury (SCI) repair. (A) The adverse microenvironment at the site of SCI induces NSCs to differentiate into astrocytes rather than neurons. (B) Transplantation of NeuroRegen scaffold combined with CBD–EGFR-Fab promotes NSC differentiation into mature neurons that form a neuronal relay to bridge the injury gap and thus promote functional recovery in animals with SCI.