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. 2017 Oct 24;12(10):e0186718. doi: 10.1371/journal.pone.0186718

Fig 2. miR-27a increases tube formation of HLECs on Matrigel and promotes migration of HLECs.

Fig 2

(A and B) Representative phase-contrast photographs and quantification of capillary-like tube formation in control or miR-27a mimic transfected HLECs (A) and control or miR-27a inhibitor transfected HLECs (B). Tube formation was quantified by the length of tubes. (C and D) Representative phase-contrast photographs and quantification of Transwell cell migration of control or miR-27a mimic transfected HLECs (C) and control or miR-27a inhibitor transfected HLECs (D). (E and F) Real-time qPCR analysis of Prox-1 expression in miR-27a mimic transfected HLECs or control (E) and miR-27a inhibitor transfected HLECs or control (F). Bars, means ± SD from 3 independent experiments. *P < 0.05, **P < 0.01, versus expression in negative control.