Skip to main content
. 2017 Oct 24;12(10):e0186587. doi: 10.1371/journal.pone.0186587

Fig 5. Fibrotic genes expression of ear and dorsal skin in a mouse by TGF-β injection.

Fig 5

TGF-β (500 ng/20 μL) or vehicle was intradermally injected 3 or 5 times in the ear (A) or dorsal skin (B) of mice. mRNA expression of α-Sma, Col1a1 and Col1a2 in the ear was measured 3 or 5 days after final TGF-β administration was evaluated. Gene expression levels (normalized to Gapdh) are expressed as the fold change of vehicle-treated control. Values are mean ± SE (n = 2–5). #p<0.05 compared to PBS-injected normal mice, *p<0.05 compared to PBS-injected normal mice.