Table 2. The predominant antigenic variants of fHbp, NHBA, NadA and PorA identified in VIC and WA (2008–2012).
Australian State | Antigen | No. of unique peptide variants | Most prevalent variant | |
---|---|---|---|---|
Peptide variant | Number (%) | |||
VIC (n = 131) |
fHbp | 30 | fHbp-1.4 | 16 (12) |
NHBA | 20 | NHBA-2 | 36 (27) | |
NadA | 7 | no peptidea | 108 (82) | |
PorA | 30 | P1.7,16–26 | 17 (13) | |
WA (n = 70) |
fHbp | 22 | fHbp-2.19 | 13 (19) |
NHBA | 21 | NHBA-3; NHBA-43 | 11 (16) | |
NadA | 6 | no peptidea | 58 (83) | |
PorA | 28 | P1.22,14–6 | 11 (16) |
aIncludes isolates in which the nadA gene was either not detected or the gene contained a frame-shift mutation or an insertion element.