Table 3. Prevalence of the exact antigenic variants of fHbp, NHBA, NadA and PorA incorporated in the Bexsero® vaccine.
| All Serogroups | Serogroup B | |||||
|---|---|---|---|---|---|---|
| Antigen | VIC (n = 131) |
WA (n = 70) |
VIC (n = 111) |
WA (n = 59) |
||
| Number (%) | Number (%) | p-value | Number (%) | Number (%) | p-valueb | |
| fHbp-1.1 | 3 (2) | 4 (6) | 0.14 | 3 (3) | 4 (7) | 0.14 |
| NHBA-2 | 36 (27) | 7 (10) | 0.002 | 36 (32) | 7 (12) | 0.002 |
| NadA-2/3.8 | 0 (0) | 0 (0) | 1 | 0 (0) | 0 (0) | 1 |
| P1.7–2,4 | 15 (11) | 5 (7) | 0.13 | 12 (11) | 5 (8) | 0.19 |
| Eithera | 43 (33) | 12 (17) | 0.008 | 40 (36) | 12 (20) | 0.015 |
aIncludes isolates possessing alleles for either one or more exact antigenic variants of the vaccine antigens.
bThe p-value was calculated using the Fisher’s exact test.