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. 2017 Oct 24;12(10):e0185676. doi: 10.1371/journal.pone.0185676

Table 4. Ethnicity, sex, and age-specific per-person and population-based QALY losses due to OA, assuming 90% moderate pain for subjects in pain not due to OA.

Ethnicity Sex Age Proportion with knee OA QALE in persons without knee OA QALE in persons with knee OA Per-person QALY losses in persons with knee OA* Population-based QALE losses in persons with knee OA
Non-Maori M 40–44 0.012 28.82 22.34 6.48 10551.97
45–49 0.048 25.39 19.84 5.55 35422.91
50–54 0.048 22.02 17.29 4.73 26514.94
55–59 0.063 18.77 14.74 4.03 27745.57
60–64 0.063 15.63 12.31 3.32 17814.60
65–69 0.114 12.69 9.99 2.70 21586.74
70–74 0.114 9.90 7.81 2.09 12914.12
75–79 0.127 7.41 5.85 1.57 9131.25
80–84 0.128 5.39 4.24 1.15 4341.30
Total 15.54 12.20 3.34 166023.41
F 40–44 0.008 31.33 24.03 7.30 8426.69
45–49 0.045 27.92 21.52 6.40 39248.26
50–54 0.045 24.53 18.96 5.57 29815.42
55–59 0.105 21.19 16.37 4.82 56407.82
60–64 0.104 17.92 13.85 4.06 36980.56
65–69 0.170 14.73 11.43 3.30 41482.76
70–74 0.169 11.61 9.06 2.55 25454.77
75–79 0.216 8.75 6.84 1.92 22157.55
80–84 0.215 6.32 4.95 1.37 12593.97
Total 15.77 12.22 3.55 272567.81
Maori M 40–44 0.009 23.41 18.49 4.93 814.83
45–49 0.029 20.28 16.12 4.15 2002.33
50–54 0.029 17.27 13.76 3.51 1303.93
55–59 0.097 14.47 11.52 2.95 2890.25
60–64 0.097 11.97 9.52 2.45 1610.46
65–69 0.144 9.76 7.74 2.02 1575.02
70–74 0.144 7.68 6.10 1.58 760.76
75–79 0.208 5.82 4.60 1.22 455.82
80–84 0.208 4.33 3.40 0.93 148.57
Total 12.64 10.05 2.60 11561.96
F 40–44 0.013 26.14 20.40 5.74 1578.25
45–49 0.048 22.86 17.92 4.94 4433.65
50–54 0.048 19.72 15.47 4.24 2858.42
55–59 0.070 16.75 13.10 3.65 2767.53
60–64 0.070 13.98 10.91 3.07 1577.79
65–69 0.131 11.50 8.97 2.53 1965.30
70–74 0.131 9.16 7.18 1.98 984.28
75–79 0.183 7.04 5.51 1.53 669.54
80–84 0.183 5.22 4.10 1.12 252.13
Total 15.55 12.17 3.38 17086.88
Totals: 15.57 12.14 3.44 467,240

QALE = quality-adjusted life expectancy; QALY = quality-adjusted life year; OA = osteoarthritis

*The expected QALE if persons with knee OA didn’t have knee OA was used to determine the per-person QALY losses. It was calculated by weighting the QALE of persons without knee OA according to the age distribution of people with knee OA.