Table 1.
1 | Males or females ≥18 years of age |
2 | Patients with dry eye disease due to mild to moderate MGD as determined by: |
• TFBUT ≤10 s | |
• OSDI© ≥16 and ≤55 | |
• Schirmer I Test ≥2 mm | |
• Sum of peripheral corneal and conjunctival staining ≤grade 10 (Oxford grading scale, both eyes combined) | |
• Altered secretion and expressibility of the Meibomian glands | |
3 | Ability and willingness to apply eyelid hygiene for at least 14 days before enrollment |
4 | Patients must be under stable therapy (both topically and systemically) for at least 4 weeks before enrollment |
5 | Ability and willingness to provide written informed consent before enrollment |
6 | Ability and willingness to participate in all examinations |
7 | Ability and willingness to understand and fill in the OSDI questionnaire |
8 | Willingness and ability to return for the follow-up assessment at week 7 (weeks 6–8) |
MGD, Meibomian gland dysfunction; OSDI, Ocular Surface Disease Index; TFBUT, tear film breakup time.