Table 1. Baseline characteristics and clinical presentation in patients with polymicrobial bloodstream infection and monomicrobial bloodstream infection.
| Characteristic | PBSI N = 194(%) |
MBSI N = 1702 (%) |
P value |
|---|---|---|---|
| Age (years, median, range) | 61 (14–90) | 60 (21–84) | 0.71 |
| Male sex | 122 (62.9) | 1039 (61) | 0.618 |
| Haematological malignancy | 116 (59.8) | 1012 (59.5) | 0.939 |
| Haematopoietic stem cell transplant (HSCT) | 26 (13.5) | 288 (16.9) | 0.261 |
| Chronic advanced cancer | 68 (39.3) | 563 (38.7) | 0.881 |
| Other comorbidities | 81 (41.8) | 609 (35.8) | 0.101 |
| MASCC score < 21 | 45 (45.6) | 291 (38.3) | 0.173 |
| Neutropenia (<500 n/μL) | 104 (53.6) | 766 (45) | 0.023 |
| Community acquired | 16 (8.2) | 179 (10.5) | 0.324 |
| Previous antibiotics (1 month) | 96 (50) | 822 (48.4) | 0.682 |
| Previous chemotherapy (1 month) | 145 (74.7) | 1195 (70.3) | 0.193 |
| Previous corticosteroid therapy (1 month) | 83 (42.8) | 609 (35.8) | 0.056 |
| Previous hospital admission (3mo) | 100 (52.1) | 842 (49.7) | 0.527 |
| Biliary stenting | 31 (16) | 82 (4.8) | <0.001 |
| Other previous manipulations | 18 (9.3) | 146 (8.6) | 0.746 |
| Source of BSI | |||
| Cholangitis | 39 (20.1) | 149 (8.8) | <0.001 |
| Other abdominal site infections. | 26 (13.4) | 138 (8.1) | 0.013 |
| Neutropenic enterocolitis | 11 (5.7) | 45 (2.6) | 0.018 |
| Perirectal infection | 7 (3.6) | 15 (0.9) | 0.005 |
| Urinary tract | 5 (2.6) | 197 (11.6) | <0.001 |
| Respiratory tract | 4 (2.1) | 165 (9.7) | <0.001 |
| Endogenous source | 52 (26.8) | 369 (21.7) | 0.104 |
| Catheter related | 28 (14.4) | 349 (20.5) | 0.045 |
| Mucositis | 3 (1.5) | 58 (3.4) | 0.2 |
| Skin and soft tissue | 2 (1) | 50 (2.9) | 0.162 |
| Unknown | 14 (7.2) | 131 (7.7) | 0.811 |
| Fever ≥38°C | 164 (84.5) | 1426 (84.4) | 0.969 |