Table 5. Risk factors for overall case-fatality rate by univariate and multivariate analysis.
| Characteristics | Survived n = 132 (%) |
Died n = 62 (%) |
p-Value | Adjusted OR (95% CI) | p-Value |
|---|---|---|---|---|---|
| Sex (male) | 82 (62.1) | 40 (64.5) | 0.957 | 1.51 (.965–2.38) | 0.071 |
| Age (years, median, range) | 60 (14–89) | 63 (21–90) | <0.001 | 0.101 (.99–1.03) | 0.148 |
| Solid tumor | 48 (36.4) | 31 (50) | 0.071 | 1.44 (.79–2.61) | 0.226 |
| MASCC risk score< 21* | 26 (34.7) | 19 (79.2) | <0.001 | 0.283 (.17-.46) | <0.001 |
| Corticosteroid therapy | 49 (37.1) | 34 (54.8) | 0.020 | 1.72 (1.1–2.7) | 0.019 |
| Persistent bacteremia | 13 (10.2) | 10 (23.3) | 0.029 | 3.4 (1.82–6.33) | <0.001 |
| Respiratory source | 0 | 4 (6.5) | 0.010 | 1.16 (0.48–2.79) | 0.74 |
| Septic Shock | 11 (8.3) | 13 (21) | 0.013 | 2.65 (1.514–4.66) | 0.001 |
| Inadequate empirical antibiotic therapy | 98 (74.2) | 40 (65.5) | 0.215 | ||
| Malignancy-related complications | 27 (20.5) | 25 (40.3) | 0.004 | 1.87 (.52–6.74) | 0.34 |
| Multidrug-resistant bacteria | 27 (20.5) | 13 (21) | 0.934 |
*MASCC: Multinational Association for Supportive Care in Cancer