Table 1.

The binding affinities between Hsp47, FKBP65, and collagens

The results are shown as the mean ± S.D.

Interaction	Kd	References
	μm
Hsp47-FKBP65	3.7 ± 2.2a	Fig. 2C
FKBP65-type I collagenb	24.7 ± 11.3c	Fig. 5D
Hsp47-type I collagenb	4.08 ± 2.8	Ref. 53
Hsp47-collagens	0.94d	Refs. 53 and 64
Hsp47-SH3 of TANGO1	0.26 ± 0.09	Ref. 37

^a Data were calculated by a global fit of the concentration-dependent measurements using the Langmuir model.

^b Type I collagen was treated by pepsin.

^c Data were calculated by a steady state fit from the concentration-dependent measurements.

^d 0.94 μm is the average K_d value between Hsp47 and type I, II, III, IV, V, VI, and X collagens from Refs. 53 and 64.