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. 2017 Oct 24;12(10):e0186567. doi: 10.1371/journal.pone.0186567

Table 2. Cox proportional hazards model for analysis of disease-free survival.

Univariate analysis Multivariate analysis
Variable Category HR 95%CI P value HR 95%CI P value
Sex Male/female 1.610 0.9061–2.917 0.1039
Smoking Ever/never 0.9400 0.4711–1.877 0.8622
Surgical procedure Lobectomy/Wedge resection 0.6326 0.2484–1.360 0.2123 0.489 0.230–1.041 0.064
Pathologic stage IA/IB 0.3445 0.1433–0.511 < 0.0001 0.382 0.206–0.709 0.002
Histology Low/intermediate, high 0.3923 0.196–0.668 0.0012 0.465 0.252–0.859 0.015
EGFR mutation Mutant/wild 1.353 0.6939–2.539 0.3941

CI, confidence interval; EGFR, epidermal growth factor receptor; HR, hazard ratio.