REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Anti-mouse CD3 (clone 145-2C11)	Biolegend	100306
Anti-mouse CD4 (clone RM4.5)	Biolegend	100566
Anti-mouse CD5 (clone 53-7.3)	Biolegend	100606
Anti-mouse CD11b (clone M1/70)	Biolegend	101224
Anti-mouse CD11c (clone N418)	Biolegend	117312
Anti-mouse CD19 (clone 6D5)	Biolegend	11506
Anti-mouse CD25 (clone PC61)	Biolegend	102038
Anti-mouse CD45 (clone 30-F11)	Biolegend	103128
Anti-mouse CD49b (clone DX5)	eBioscience	11-5971-85
Anti-mouse CD127 (clone A7R34)	Biolegend	135013
Anti-mouse ICOS (clone 15F9	eBioscience	46-9940-82
Anti-mouse GR1 (clone RB6-8C5)	Biolegend	108406
Anti-mouse IL-5 (clone TRFK5	Biolegend	504304
Anti-mouse IL-13 (clone eBio13A)	eBioscience	25-7133-82
Anti-mouse Ly6G (clone 1A8)	Biolegend	127616
Anti-mouse SiglecF (clone ES22-10D8)	Miltenyi	130-102-274
Anti-mouse ST2 (clone RMST2-2)	eBioscience	17-9335-82
Anti-mouse TER119 (clone TER-119)	Biolegend	116220
Anti-HMGB-1 rabbit polyclonal	Abcam	Ab18256
Anti-c-myc (clone Myc.A7)	Thermo Fisher Scientific	MA1-21316
Anti-human IL-33 goat polyclonal	R&D Systems	AF3625
Anti-mouse IL-33 goat polyclonal	R&D Systems	AF3626
Anti-mouse IL-1α	R&D Systems	AF-400-NA
IgG1 isotype control antibody (clone MOPC-21)	Produced in-house	N/A
Bacterial and Virus Strains
Heligmosomoides polygyrus	(Johnston et al, 2015)	N/A
Nippostrongylus brasiliensis	(Lawrence et al, 1996)	N/A
Biological Samples
Human lung tissue	Lothian NRS Bioresource	15/ES/0094
Chemicals, Peptides, and Recombinant Proteins
Recombinant mouse IL-1α	Biolegend	575002
Recombinant mouse IL-33	Biolegend	580506
Recombinant human IL-33	Biolegend	581806
ST2-Fc	Biolegend	557904
Dynabeads Protein G	Thermo Fisher Scientific	10004D
Proteinase K	Sigma	557904
DNAse (protease-free)	Sigma	4536282001
Liberase TL	Sigma	05401020001
Methylcholine chloride	Sigma	A2251
Hoescht 33342	Thermo Fisher Scientific	H3570
Critical Commercial Assays
Mouse IL-33 Duoset ELISA	R&D systems	DY3626
Human IL-33 Duoset ELISA	R&D systems	DY3625B
Annexin V Apoptosis Detection Kit	eBioscience	88-8005-72
Limulus Amoebocyte Lysate assay	Lonza	QCL-1000
Experimental Models: Cell Lines
HEK293T	ATCC	CRL-3216
CMT-64	ECACC	10032301
Experimental Models: Organisms/Strains
Mouse: IL-13-eGFP (C57BL/6J)	(Neill et al., 2010)	N/A
Mouse: hIL-33+/+ / mIL-33–/– (humanized IL-33) (BALB/c)	(Cohen et al., 2015)	N/A
Recombinant DNA
pSecTAG2A plasmid	Thermo Fisher Scientific	V90020
Software and Algorithms
ClustalX	(Thompson et al., 1997)	www.clustal.org
Mascot v2.4	Matrix Science	www.matrixscience.com
SMART	(Letunic et al., 2015)	smart.embl-heidelberg.de/
HHpred	(Söding, 2005)	toolkit.tuebingen.mpg.de/#/tools/hhpred
Modeller v9.12	(Sali and Blundell, 1993)	salilab.org/modeller/
APBS	(Baker et al, 2001)	www.poissonboltzmann.org/
ESPript v3	(Robert and Gouet, 2014)	espript.ibcp.fr/
PyMOL	Schrödinger, LLC	www.pymol.org
PROSITE	(de Castro et al., 2006)	prosite.expasy.org/
Protein Data Bank	(Berman et al., 2000)	www.rcsb.org/pdb
Wormbase ParaSite	(Howe et al., 2016)	parasite.wormbase.org/
FlowJo v9.1	Flowjo, LLC	www.flowjo.com/
Prism v7	Graphpad Software	www.graphpad.com/scientific-software/prism/
BIAcore T200 software v2.01	GE Healthcare	N/A
Other
Superdex 200 10/300 GL	GE Healthcare	17517501
MonoQ 5/50 GL	GE Healthcare	17-5166-01
Series S Sensor Chip NTA	GE Healthcare	BR-1005-32