Table 2.
Proportion of clinical parasite isolates binding to various endothelial receptors.
| Receptor | n | IE count >0 (%) | IE count >20 (%) | mean binding (range) |
|---|---|---|---|---|
| CD36 | 2904 | 79.9 | 57.5 | 136.0 (0–9997) |
| TSP | 2216 | 35.4 | 11.0 | 11.5 (0–1160) |
| ICAM-1 | 2901 | 47.4 | 24.0 | 27.5 (0–2752) |
| E-selectin | 2901 | 36.4 | 11.8 | 9.8 (0–841) |
| P-Selectin | 2897 | 35.3 | 13.5 | 12.1 (0–1093) |
| PECAM-1 | 2480 | 33.1 | 12.0 | 8.6 (0–429) |
| VCAM-1 | 2898 | 17.6 | 2.3 | 2.4 (0–903) |
| CSA | 2894 | 16.4 | 1.3 | 1.4 (0–562) |
| EPCR | 723 | 21.0 | 1.9 | 2.1 (0–240) |
| Integrin α5β1 | 2862 | 36.0 | 14.6 | 11.4 (0–498) |
| Vitronectin | 2499 | 21.6 | 2.5 | 2.0 (0–184) |
| C. fibronectin | 2901 | 35.7 | 9.7 | 6.4 (0–665) |
| Laminin | 2899 | 26.7 | 5.2 | 4.1 (0–376) |
| Integrin α3β1 | 2897 | 34.6 | 12.8 | 10.2 (0–1131) |
| Integrin αvβ3 | 2861 | 54.6 | 29.8 | 30.3 (0–1378) |
| JAM-A | 2502 | 19.5 | 1.8 | 1.5 (0–97) |
| JAM-B | 2439 | 38.3 | 16.0 | 15.4 (0–1344) |
| VE-cadherin | 2709 | 37.9 | 14.7 | 14.0 (0–1164) |
| ICAM-2 | 2873 | 37.8 | 12.1 | 12.0 (0–1040) |