Table 4.
Associations of the course of neonatal hair glucocorticoid concentrations with perinatal and maternal factors.
| Effect on delta | Effect on OPV values | ||||
|---|---|---|---|---|---|
| β (95% CI) | P value | β (95% CI) | P value | ||
| Perinatal factors | |||||
| Gestational age | Cortisol | −0.02 (−0.05 to 0.00) | 0.08 | 0.08 (0.04 to 0.12) | <0.001 |
| Cortisone | −0.006 (−0.013 to 0.001) | 0.08 | 0.00 (−0.04 to 0.04) | 0.87 | |
| Birth weight (in kg) | Cortisol | −0.05 (−0.12 to 0.02) | 0.19 | 0.13 (0.003 to 0.26) | 0.05 |
| Cortisone | −0.02 (−0.03 to 0.01) | 0.15 | 0.00 (−0.12 to 0.12) | 0.96 | |
| Male sex | Cortisol | 0.02 (−0.07 to 0.11) | 0.68 | 0.19 (0.02 to 0.36) | 0.03 |
| Cortisone | −0.01 (−0.03 to 0.02) | 0.46 | 0.00 (−0.14 to 0.13) | 0.99 | |
| Delivery via caesarian section | Cortisol | 0.06 (−0.04 to 0.16) | 0.24 | −0.06 (−0.25 to 0.13) | 0.55 |
| Cortisone | 0.03 (0.01 to 0.05) | 0.02 | −0.08 (−0.23 to 0.08) | 0.33 | |
| Perinatal infection (≥7 days antibiotics) | Cortisol | −0.06 (−0.15 to 0.04) | 0.25 | −0.04 (−0.22 to 0.14) | 0.66 |
| Cortisone | −0.03 (−0.05 to −0.004) | 0.02 | 0.12 (−0.03 to 0.27) | 0.11 | |
| Maternal factors | |||||
| Parity | Cortisol | 0.07 (−0.02 to 0.16) | 0.11 | −0.11 (−0.28 to 0.05) | 0.18 |
| Cortisone | 0.01 (−0.01 to 0.03) | 0.32 | 0.01 (−0.13 to 0.14) | 0.91 | |
Values represent log-transformed β (95% confidence interval) as calculated with linear regression. All associations were corrected for age at the OPV.
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