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. 2017 Sep 25;6(8):R162–R170. doi: 10.1530/EC-17-0246

Table 4.

Results of the studies assessing the efficacy of GnRHa given before and during chemotherapy in HSCT recipients in terms of ovarian function and fertility preservation.

Reference No of patients Previous Cxt Type of HSCT Type of disease Results
Blumenfeld, 2012 83 Allo/auto Various 18/47 in GnRHa group vs 4/36 in control group
33 Auto Lymphoma 14/21 in GnRHa group vs 2/11 in control group
Cheng, 2012 44 Yes (42/44) Allo/auto Various 7/44
29 Allo Allo HSCT 2/29, P = 0.04
15 Auto HSCT 5/15
Pup, 2014 17 Auto Lymphoma 5/17
Phelan, 2016 17 (7 received GnRHa) Yes Auto/allo Various 3/7
Demesteere, 2016 10 (3 received GnRHa) No Auto Lymphoma 2/3 in GnRHa group vs 4/7 in control group

HSCT, hematopoietic stem cell transplantation.