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. 2017 Oct 24;7:22. doi: 10.1186/s13395-017-0139-5

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Assessment of mitochondria-associated cell signalling in C57BL/10, mdx, dko and mdx-Fiona mice. Representative images and quantification of a Sirtuin 1 (Sirt 1), normalised to loading control (total protein stain; TPS), and b phosphorylation status of AMP-activated protein kinase (AMPK), normalised to total protein expression of AMPK, in quadriceps muscles from C57BL/10 (C57), mdx, dko and mdx-Fiona (mdx-Fio) mice. Gene expression of c proliferator-activated receptor gamma coactivator (PGC) -1α and d PGC-1β in tibialis anterior muscles from C57, mdx, dko and mdx-Fio mice. Data are represented as mean ± SEM, * denotes significance set at P < 0.05. Representative image n = 3/group, quantification generated from n = 5-6/group