Table 2.
Potential miRNA biomarkers for CRC screening
| miRNA | Blood or stool | Sensitivity (%) | Specificity (%) | Citation |
|---|---|---|---|---|
| miR-92a | Blood and stool | 72–79 (blood) 72 (stool) |
59–69 (blood) 73 (stool) |
[60, 66] |
| miR-20a | Blood and stool | 46 (blood) 55 (stool) |
73 (blood) 82 (stool) |
[46, 67] |
| miR-21 | Blood and stool | 62–85 (blood) 56 (stool) |
79–88 (blood) 73 (stool) |
[52, 55, 66] |
| miR-221 | Blood and stool | 86 (blood) 62 (stool) |
41 (blood) 74 (stool) |
[51, 68] |
| miR-18a | Stool | 61 | 69 | [68] |
| miR-135b | Stool | 78 | 68 | [66] |
| miR-144* | Stool | 74 | 87 | [67] |
| miR-199a-3p | Blood | 48 | 75 | [50] |
| miR-155 | Blood | 58 | 95 | [48] |
| miR-183 | Blood | 74 | 89 | [56] |
| miR-29a | Blood | 53–65 | 85–93 | [57] |
| miR-29b | Blood | 61 | 73 | [47] |
| miR-210 | Blood | 75 | 74 | [53] |
| miR-196b | Blood | 63 | 87 | [54] |
| miR-139-3p | Blood | 97 | 98 | [49] |
| miR-622 | Blood | 88 | 64 | [49] |
| miR-506 | Blood | 61 | 77 | [72] |
| miR-4316 | Blood | 75 | 77 | [72] |