Table 2.
Summary of hematology results
| Sex | ID | WBC 103/mL | RBC 106/mL | HGB g/dL | HCT % | MCV fL | MCH pg | MCHC g/dL | PLT 103/mL | NEUT %WBC | LYM %WBC | MONO %WBC | EOS %WBC | BASO %WBC | LUC %WBC | Abs. NEUT 103/mL | Abs. LYM 103/mL | Abs. MONO 103/mL | Abs. EOS 103/mL | Abs. BASO 103/mL | Abs. LUC 103/mL) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pre | |||||||||||||||||||||
| Male | RQ8571 | 13.22 | 5.85 | 14.6 | 44.3 | 75.6 | 25.0 | 33.1 | 435 | 39.9 | 55.9 | 1.7 | 0.3 | 0.7 | 1.5 | 5.28 | 7.39 | 0.23 | 0.04 | 0.09 | 0.19 |
| RQ8872 | 5.56 | 5.87 | 14.8 | 46.2 | 78.7 | 25.3 | 32.1 | 310 | 44.5 | 52.3 | 1.5 | 0.1 | 0.7 | 0.9 | 2.47 | 2.91 | 0.08 | 0.01 | 0.04 | 0.05 | |
| Female | RQ8425 | 9.40 | 5.87 | 14.1 | 42.6 | 72.6 | 23.9 | 33.0 | 291 | 28.1 | 64.7 | 4.1 | 1.0 | 0.9 | 1.3 | 2.64 | 6.08 | 0.39 | 0.09 | 0.08 | 0.12 |
| RQ8676 | 8.88 | 5.56 | 14.1 | 42.3 | 76.0 | 25.4 | 33.5 | 257 | 67.3 | 29.7 | 1.9 | 0.4 | 0.4 | 0.4 | 5.98 | 2.63 | 0.17 | 0.03 | 0.03 | 0.04 | |
| Pre | |||||||||||||||||||||
| Male | RQ8571 | 14.00 | 5.54 | 13.9 | 42.6 | 77.0 | 25.0 | 32.5 | 410 | 20.8 | 74.2 | 1.9 | 1.1 | 0.5 | 1.5 | 2.91 | 10.38 | 0.27 | 0.15 | 0.07 | 0.21 |
| RQ8872 | 4.47 | 5.59 | 14.3 | 46.2 | 82.6 | 25.6 | 31.0 | 267 | 24.2 | 72.4 | 2.1 | 0.2 | 0.2 | 1.0 | 1.08 | 3.23 | 0.09 | 0.01 | 0.01 | 0.04 | |
| Female | RQ8425 | 11.28 | 5.69 | 13.8 | 43.5 | 76.3 | 24.2 | 31.7 | 332 | 14.2 | 78.5 | 4.0 | 0.9 | 0.6 | 1.8 | 1.60 | 8.85 | 0.45 | 0.11 | 0.07 | 0.20 |
| RQ8676 | 8.28 | 5.36 | 13.6 | 42.0 | 78.3 | 25.4 | 32.5 | 280 | 61.2 | 34.6 | 2.4 | 0.9 | 0.3 | 0.6 | 5.07 | 2.87 | 0.20 | 0.07 | 0.02 | 0.05 | |
| Post | |||||||||||||||||||||
| Male | RQ8571 | 12.51 | 5.34 | 13.6 | 41.3 | 77.3 | 25.4 | 32.8 | 385 | 48.6 | 45.4 | 3.8 | 0.6 | 0.3 | 1.3 | 6.07 | 5.67 | 0.48 | 0.08 | 0.04 | 0.16 |
| RQ8872 | 5.39 | 6.11 | 15.9 | 50.5 | 82.6 | 26.1 | 31.6 | 243 | 34.0 | 63.2 | 1.3 | 0.1 | 0.3 | 1.1 | 1.84 | 3.40 | 0.07 | 0 | 0.02 | 0.06 | |
| Female | RQ8425 | 10.03 | 5.82 | 14.3 | 44.0 | 75.6 | 24.5 | 32.5 | 261 | 16.7 | 72.5 | 4.9 | 3.9 | 0.4 | 1.5 | 1.68 | 7.28 | 0.49 | 0.39 | 0.04 | 0.16 |
| RQ8676 | 15.39 | 5.35 | 13.8 | 42.8 | 80.0 | 25.9 | 32.4 | 280 | 82.8 | 14.4 | 1.9 | 0.2 | 0.3 | 0.4 | 12.75 | 2.21 | 0.30 | 0.03 | 0.04 | 0.06 | |
Blood samples were collected within 30 days prior to adeno-associated virus administration and on the day of necropsy.
Abs. BASO, Absolute Basophil count; Abs. EOS, absolute eosinophil count; Abs. LUC, absolute large unstained cell count; Abs. LYM, absolute lymphocyte count; Abs. MONO, absolute monocyte count; Abs. NEUT, absolute neutrophil count; BASO, basophils; EOS, eosinophils; HGB, hemoglobin; HCT, hematocrit; ID (animal), (animal) identification number; LUC, large unstained cells; LYM, lymphocytes; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MCV, mean corpuscular volume; MONO, monocytes; NEUT, neutrophils; PLT, platelet count; RBC, red blood cell Count.