Table 3.
Comparison between QuaDMutEx and other methods. For QuaDMutEx, we used default parameter values k=1 and C=1 unless specified otherwise
| Method | Genes | Coverage | Excess | Dendrix |
|---|---|---|---|---|
| coverage | score | |||
| GBM: Glioblastoma multiforme | ||||
| TiMEx | 3 | 0.7857 | 0.0606 | 62 |
| RME | 3 | 0.7857 | 0.0606 | 62 |
| CoMEt | 5 | 0.8452 | 0.0845 | 65 |
| Dendrix | 9 | 0.8571 | 0.0556 | 68 |
| QuaDMutEx (C=0.5) | 12 | 0.9286 | 0.0769 | 72 |
| QuaDMutEx | 7 | 0.8690 | 0.0822 | 67 |
| OV: Ovarian Cancer | ||||
| TiMEx | 2 | 0.9525 | 0 | 301 |
| RME | 5 | 0.9494 | 0.1 | 62 |
| CoMEt | 2 | 0.9525 | 0 | 301 |
| Dendrix | 3 | 0.9557 | 0 | 302 |
| QuaDMutEx | 3 | 0.9557 | 0 | 302 |
| LUNG: Lung Adenocarcinoma | ||||
| TiMEx | 2 | 0.5521 | 0 | 90 |
| RME | 3 | 0.6748 | 0.1273 | 96 |
| CoMEt | 6 | 0.6196 | 0 | 101 |
| Dendrix | 12 | 0.6809 | 0.0270 | 108 |
| QuaDMutEx | 15 | 0.8160 | 0.1053 | 119 |
| BRCA: Breast Invasive Carcinoma | ||||
| TiMEx | 3 | 0.4202 | 0.1006 | 289 |
| RME | 3 | 0.3865 | 0.0268 | 290 |
| CoMEt | 3 | 0.2620 | 0 | 202 |
| Dendrix | 29 | 0.5811 | 0.09598 | 402 |
| QuaDMutEx (C=1.5) | 20 | 0.6109 | 0.1338 | 408 |
| QuaDMutEx | 26 | 0.6342 | 0.1595 | 411 |
Highest result for each dataset indicated in italics