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. 2017 Oct 24;19:117. doi: 10.1186/s13058-017-0902-x

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Example patient with a malignant lesion. a T1 MRI; b DCE MRI; c T2 MRI; d,e reconstructed HbT images with DCE-guided and T2-guided methods, respectively. Reconstructed images are overlaid on the T1 MRI cross-section. DCE dynamic contrast-enhanced, HbT total hemoglobin, MRI magnetic resonance imaging, NIRST near-infrared spectral tomography