Table 2.
Groups | LVEF (%) | FS (%) | LVEDd (mm) | CO (L/min) |
---|---|---|---|---|
Sham | 89.25 ± 2.52 | 42.33 ± 2.56 | 5.67 ± 2.12 | 0.232 ± 0.018 |
CME | 52.63 ± 1.78a | 36.25 ± 3.22a | 6.51 ± 3.33a | 0.192 ± 0.033a |
AAV-Nrf2 (CME) | 70.44 ± 3.21ab | 44.74 ± 1.58ab | 5.79 ± 1.66ab | 0.255 ± 0.025ab |
AAV-control (CME) | 52.87 ± 2.12a | 34.55 ± 2.24a | 6.48 ± 1.85a | 0.201 ± 0.011a |
Data is shown as Mean ± SD
AAV-Nrf2(CME) rats injected Nrf2 undergone CME operation, AAV-control (CME) rats injected AAV-control undergone CME operation, CME coronary microembolization, LVEF left ventricular ejection fraction, FS fractional shortening, LVEDd left ventricular end -diastolic diameter, CO cardiac output, Nrf2 nuclear factor erythroid 2-like, AAV adeno-associated virus
a P < 0.05 contrasted with sham
b P < 0.05 contrasted with CME or AAV control (CME)