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MiR-1296-5p suppresses mTORC1 signaling. a, b miR-1296-5p overexpression did not alter the activation of RhoA and Rac1 in SK-BR-3 breast cancer cells. The RhoA or Rac1 relative active levels were normalized to the average value of SK-BR-3 cells transfected with control miRNA. ns, no significance. c, d miR-1296-5p overexpression suppresses the phosphorylation of S6 in SK-BR-3 or BT-474 breast cancer cells
