Table 5.
Comparison of Present Study With Phase III Studies of Capecitabine With Trastuzumab or Lapatinib
| Treatment Regimen | Source | PFS, mo | RR, % | OS, mo |
|---|---|---|---|---|
| Cap | Geyer et al (23) | 4.4 | 15 | NR |
| Cap and lapatinib | Geyer et al (23) | 8.4 | 22 | NR |
| Cap | von Minckwitz et al (21) | 5.6 | 27 | 20.4 |
| Cap and T | von Minckwitz et al (21) | 8.4 | 48 | 24 |
| Cap, T, and V | Present study | 11.3 | 67 | 27 |
Abbreviations: Cap, capecitabine; NR, not reported; OS, overall survival; PFS, progression-free survival; RR, response rate; T, trastuzumab; V, vinorelbine.