Figure 3.
Functional assays of CapG in CRC cells. (A) CRC cells transfected with CapG-specific siRNA (siRNA) exhibited a reduced expression of CapG protein compared with corresponding cells transfected with a scrambled siRNA (control). (B) Knockdown of CapG by RNA interference inhibited wound healing. (C) Knockdown of CapG by RNA interference inhibited cell migration (magnification, ×200). *P<0.05, ***P<0.001. CapG, macrophage-capping protein; CRC, colorectal carcinoma; siRNA, small interfering RNA.