Table I.

Clinicopathological features of 200 patients with angiosarcoma.

Clinicopathological features	Total (n=200)	Viscera (n=65)	Head and neck (n=64)	Soft tissue (n=37)	Breast (n=33)
Male/female	97/103	32/33	44/20	20/17	1/32
Mean age, years	52.3	45.5	66.0	52.6	38.6
<65	137	55	25	25	31
≥65	63	10	39	12	2
Mean size, cm	5.2	6.4	4.5	4.6	5.1
<5	57	12	15	18	12
≥5	50	19	13	9	9
Unknown	93	34	36	10	12
Tumor differentiation
High grade	94	29	42	20	3
Low grade	106	36	22	17	30
Epithelioid appearance	37	14	10	13	0
Tumor recurrence/metastasis
Yes	63	21	14	16	12
No	50	15	15	9	11
Unknown	87	29	35	12	20
Metastatic site
Bone	18	11	3	3	1
Lung	18	5	2	9	2
Liver	8	6	2	0	0
Lymph node	8	4	2	2	0
Trunk	6	0	0	2	4
Parotid gland	4	0	4	0	0
Breast	3	0	0	0	3
Retroperitoneum	2	2	0	0	0
Pleura	1	1	0	0	0
Spleen	1	1	0	0	0
Treatment modality
Multimodal therapy	56	18	11	13	14
Surgery + radiotherapy	18	5	5	4	4
Surgery + chemotherapy	33	12	5	9	7
Surgery + radiotherapy + chemotherapy	5	1	1	0	3
Non-multimodal therapy	67	22	20	14	11
Surgery	64	21	18	14	11
Radiotherapy	2	1	1	0	0
Chemotherapy	1	0	1	0	0
Unknown	77	25	33	10	8
Survival, %
5-year disease-free survival	19.3	19.0	0	18.7	34.8
5-year overall survival	40.8	37.0	28.0	36.6	87.5