Table 2. Sequential boryl substitution/Suzuki–Miyaura coupling ^a .

^aIsolated yields.

^b1-Iodo-4-nitrobenzene, K₂CO₃ (2.0 equiv.) and Pd(PPh₃)₄ (10 mol%) were used in a 10 : 1 (v/v) mixture of DMF and H₂O at 100 °C.

^cIodobenzene, K₂CO₃ (2.0 equiv.) and Pd(PPh₃)₄ (10 mol%) were used in a 10 : 1 (v/v) mixture of DMF and H₂O at 100 °C.

^d4-Iodoanisole, K₃PO₄ (2.55 equiv.), PCy₃ (3.6 mol%) and Pd₂(dba)₃·CHCl₃ (1.5 mol%) were used in a 3 : 1 (v/v) mixture of 1,4-dioxane and H₂O at 100 °C.