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. 2017 Sep 6;14(5):5393–5399. doi: 10.3892/ol.2017.6900

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Copyright: © Sheng et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Interaction network of SRSF1-related genes and colon cancer associated genes. (A) Overlapping analysis of 2,678 SRSF1-related genes (identified using The Cancer Genome Atlas) and 3,625 colon cancer genes (identified using GeneCards). (B) Gene Ontology analysis (biological process) of 468 SRSF1-related colon cancer genes. Fisher exact P-values were plotted for each enriched functional category. Enriched functional categories with P<0.05 were shown. (C) Kyoto Encyclopedia of Genes and Genomes pathway of SRSF1-related colon cancer genes. Fisher exact P-values were plotted for each enriched pathway. Enriched functional pathways with P<0.05 were shown. SRSF1, serine/arginine-rich splicing factor 1; ErbB, Epidermal growth factor receptor; TGF, transforming growth factor; NOD, nucleotide-binding oligomerization domain; MAPK, mitogen-activated protein kinase; mTOR, mechanistic target of rapamycin; VEGF, vascular endothelial growth factor.