Figure 1.
Feasibility of antibody-based enrichment strategy. The tryptic peptides of in vitro nitrated BSA were subjected for anti-tyrosine antibody IP before LC-MS/MS analysis. (A) The overlap of identified nitrotyrosine peptides between replicates. (B) The enrichment of NT-containing peptides by anti-nitrotyrosine antibody. The number on each column are the number of PSM of nitrotyrosine peptides (grey) and non-nitrated peptides (black) identified from each sample. PSM, peptide spectra matched.