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. Author manuscript; available in PMC: 2017 Oct 25.
Published in final edited form as: Drug Metab Lett. 2015;9(1):48–62. doi: 10.2174/1872312809666150119110200

Fig. (8).

Fig. (8)

Time- and concentration-dependent inhibition of CYP3A4 by 39KC and 45D. Concentrations of fractions are shown on the right of the plots (A). Double-reciprocal plots of kobs and inhibitor concentrations were plotted on linear graph to determine inactivation parameters KI and kinact in plot (B). Each point represents the mean of duplicate determinations.