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. Author manuscript; available in PMC: 2017 Oct 25.
Published in final edited form as: J Med Chem. 2017 Sep 1;60(17):7524–7538. doi: 10.1021/acs.jmedchem.7b00930

Figure 1.

Figure 1

Structure of triazine core PI3K inhibitors 1, reference compound 2, reported clinical candidate 3, and pyrimidine or fused pyrimidine core containing molecules 4, 5, and 6.