Figure 3. Manhattan plot and regional association plot for the Eyes Test (females) meta-analysis GWAS.
A. Manhattan plot of the Eyes Test meta-analysis (female). X axis is the chromosomal position of the SNP, and Y axis is the negative logarithm of the P-value. The red line indicates genome-wide significant threshold of 5x10-8. Lead SNP for all loci with P < 1x10-6 is provided. n = 44,574, and λgc = 1.05. LDSR intercept = 1.05. Regional association plot of the significant locus for the Eyes Test (females) meta-analysis.