Table 2.
Characteristics of participating sentinel sites
| Site1 | Beds | Case ascertainment | Vaccination status ascertainment | Common outcome-exposure identifier | Confirmed aseptic meningitis cases2 | Confirmed ITP cases2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| (n) | ICD codes | Free text | Electronic vaccine registry | Vaccination cards | Medical records | Parents contacted3 | Unique identification number | Clinical history number | National identity card | Level 1 (n) | Level 2 (n) | Level 3 (n) | Level 1 (n) | Level 2 (n) | Level 3 (n) | |
| Albania | 240 | ICD-9 | - | ▯ | ▯ | - | - | - | ▯ | - | 1 | - | - | 5 | - | - |
| Argentina-01 | 330 | ICD-10 | - | ▯ | - | - | ▯ | - | ▯ | ▯ | 1 | - | - | 6 | - | 1 |
| Argentina-02 | 78 | ICD-10 | - | ▯ | - | - | ▯ | - | ▯ | ▯ | - | - | - | 1 | - | - |
| Argentina-03 | 380 | ICD-10 | - | ▯ | - | ▯ | ▯ | - | ▯ | ▯ | - | - | - | 4 | - | - |
| Argentina-04 | 246 | ICD-10 | - | ▯ | - | - | - | - | ▯ | ▯ | - | - | - | - | - | - |
| Argentina-05 | 224 | ICD-10 | - | ▯ | - | - | - | - | ▯ | ▯ | - | - | - | 4 | - | - |
| Argentina-06 | 61 | ICD-10 | - | ▯ | - | - | ▯ | - | ▯ | ▯ | - | - | - | 2 | - | - |
| Australia-01 | 334 | ICD-10 | - | ▯ | - | - | - | ▯ | ▯ | - | 2 | 5 | - | 5 | - | 2 |
| Australia-02 | 184 | ICD-10 | - | ▯ | ▯ | - | - | ▯ | ▯ | - | - | - | 1 | 4 | - | - |
| Chile-01 | 440 | ICD-10 | - | ▯ | - | - | - | - | - | ▯ | 3 | - | - | 2 | - | - |
| Chile-02 | 300 | ICD-10 | - | ▯ | - | - | ▯ | - | - | ▯ | 5 | - | 1 | 4 | - | - |
| Chile-03 | 704 | ICD-10 | - | ▯ | - | - | - | - | - | ▯ | - | - | - | 6 | - | - |
| Chile-04 | 876 | ICD-10 | - | ▯ | - | - | ▯ | - | - | ▯ | - | 1 | - | 5 | - | - |
| China | 500+ | ICD-10 | - | ▯ | - | - | - | - | - | - | - | - | 1 | 7 | - | - |
| Colombia | 340 | ICD-10 | - | ▯ | - | - | - | - | - | ▯ | - | - | - | 2 | - | - |
| Costa Rica | 313 | ICD-10 | - | ▯ | - | - | ▯ | - | - | ▯ | 1 | 2 | 1 | 13 | - | - |
| Honduras | 1,109 | ICD-10 | - | - | - | ▯ | ▯ | - | ▯ | ▯ | - | - | - | 1 | - | - |
| India | 1,200 | ICD-9, ICD-10 | - | - | - | ▯ | ▯ | ▯ | - | - | 3 | 5 | - | 1 | 1 | - |
| Iran-01 | 246 | ICD-10 | - | - | - | ▯ | - | - | - | - | 8 | 16 | 2 | 14 | 3 | - |
| Iran-02 | 340 | ICD-10 | - | - | - | ▯ | ▯ | - | - | - | 9 | 6 | 1 | 20 | - | - |
| Peru | 465 | ICD-10 | - | - | - | ▯ | ▯ | - | - | ▯ | - | - | - | 7 | - | - |
| Singapore | 830 | ICD-9, ICD-10 | - | ▯ | - | ▯ | - | ▯ | ▯ | ▯ | - | - | - | 17 | 1 | 2 |
| South Africa | 3,200 | ICD-10 | - | - | - | ▯ | ▯ | - | - | - | - | 1 | 2 | - | - | - |
| Spain4 | 10,987 | ICD-9 | - | ▯ | - | - | - | ▯ | - | - | 2 | - | 3 | 32 | 2 | 6 |
| Uganda | 254 | - | ▯ | - | ▯ | ▯ | ▯ | - | - | - | - | - | - | - | - | - |
| Uruguay | 245 | ICD-10 | - | ▯ | - | - | - | - | - | ▯ | 1 | - | - | 3 | - | - |
1
The study period was January 2010 to March 2014, except for Australia, which retrospectively included the first 25 most recent cases that fulfill inclusion criteria for each condition (for both sites combined)
2
Only the highest level of diagnosis certainty achieved applies. The cases correspond to confirmed cases for which a link to vaccination data was available. Confirmed cases for which vaccination status was unknown were excluded from the study
3
Parents contacted were asked to provide a copy of the vaccination cards
4
Spain was designated as one site, but included all public hospitals of the Valencia Region, its hospital beds correspond to the total number of beds from the combined hospitals