Table 2.
Comparison of biochemical composition of RBC-based and HBOC-based perfusion fluids prior to the start of perfusion
| RBC-Based Perfusate | HBOC-Based Perfusate | p value | |
|---|---|---|---|
| pH | 7.379 (7.256-7.458) | 7.685 (7.463-7.785) | 0.008 |
| PCO2 (kPa) | 4.31 (0.86-7.78) | 0.81 (0.74-2.23) | 0.087 |
| PO2 (kPa) | 28.26 (24.60-30.36) | 56.43 (45.11-64.07) | 0.008 |
| BE (mmol/L) | -13.7 (-19.1- -1.7) | -10.7 (-12.1- -9.7) | 0.691 |
| CHCO3- (mmol/L) | 17.3 (3.7-40.4) | 8.1 (7.1-11.7) | 0.691 |
| Na+ (mmol/L) | 138.6 (116.8-157.2) | 150.9 (148.3-153.6) | 0.206 |
| K+ (mmol/L) | 8.79 (6.31-12.90) | 1.90 (1.80-1.90) | 0.008 |
| Cl- (mmol/L) | 112.4 (76.0-117.0) | 109.0 (108.4-113.4) | 0.008 |
| Ca2+ (mmol/L) | 0.637 (0.573-0.700) | 1.000 (0.900-1.000) | 0.786 |
| tHb (g/L) | 84.4 (75.5-100.2) | 57.3 (55.8-58.5) 1 | 0.008 |
| O2Hb (%) | 97.8 (94.8-98.0) | 81.1 (79.3-82.9) | 0.008 |
| COHb (%) | 1.0 (0.9-1.9) | 0.1 (0.1-0.1) | 0.008 |
| H.Hb (%) | 0.7 (0.6-3.6) | 17.6 (16.8-18.6) | 0.008 |
| MetHb (%) | 0.5 (0.4-0.6) | 1.8 (1.6-2.0) | 0.008 |
| SO2 (%) | 99.3 (96.4-99.4) | 82.0 (81.0-82.9) | 0.008 |
| Hct(c) (%) | 22.6 (16.9-30.1) | 17.2 (16.8-17.5) | 0.079 |
| Glu (mmol/L) | 8.0 (6.8-10.5) | 3.5 (3.5-5.6) | 0.008 |
| Lactate (mmol/L) | 7.7 (6.7-9.2) | 5.4 (5.3-5.8) | 0.008 |
1
After 6 hours the median (range) value of Hb (g/L) was 59.3 (49.6-64.1)