Table 4.
Perfusion parameters of both perfused groups with associated p values
| RBC | HBOC | p value | |
|---|---|---|---|
| HA Pressure (mmHg) | 53.0 (36.5-56.0) | 56.6 (41.8-58.2) | 0.002 |
| HA Resistance T0 | 0.39 (0.22-0.56) | 0.26 (0.20-0.32) | 0.667 |
| HA Resistance T0-6.0 | 0.12 (0.07-0.56) | 0.11 (0.10-0.32) | 0.471 |
| HA Flow/gram (mL/min/g) | 0.26 (0.10-0.36) | 0.30 (0.09-0.32) | 0.828 |
| PV Flow/gram (mL/min/g) | 0.59 (0.29-0.65) | 0.63 (0.23-0.67) | 0.385 |
| Haemoglobin (g/dL) | 73.80 (70.54-85.80) | 56.24 (52.80-61.40) | <0.001 |
| O2ER/gram x 105 | 9.43 (3.45-13.67) | 13.75 (5.53-17.40) | 0.001 |
| Lactate level | |||
| Highest | 13.3 (5.4-20.0) | 10.1 (8.6-19.3) | 0.389 |
| Lowest | 1.4 (0.8-9.0) | 1.2 (0.3-9.1) | 0.524 |
| Last | 1.5 (0.8-20.0) | 1.6 (0.3-11.6) | 0.889 |
| Tissue ATP content (nmol/g protein) | 0.836 | ||
| T0 (preperfusion) | 3.9 (2.9) | 5.2 (6.0) | |
| T6 (postperfusion) | 18.9 (22.5) | 23.1 (32.6) | |
Abbreviations:
ATP, adenosine triphosphate; HA, Hepatic Artery; HBOC, Hemopure perfusion group; O2ER, Oxygen extraction ratio; PV, Portal Vein; RBC, Red blood cell perfusion group
Note:
T0 designates the median resistance immediately after perfusion was commenced; T0-6.0 designates the median resistance over the course of the perfusion.