Table 2. Differentially expressed canine and human miRNAs between doxorubicin sensitive and resistant canine cancer cell lines.
| miR name | logFC | P value | miR name | logFC | P value |
|---|---|---|---|---|---|
| Canine miRNAs | |||||
| cfa-let-7f | 1.24 | 0.0025 | cfa-miR-19a | 3.55 | 0.0179 |
| cfa-let-7g | 1.24 | 0.0015 | cfa-miR-19b | 2 | 0.0244 |
| cfa-miR-103 | 0.81 | 0.0436 | cfa-miR-20a | 1.54 | 0.0182 |
| cfa-miR-106a | 1.49 | 0.0181 | cfa-miR-25 | 1.16 | 0.033 |
| cfa-miR-106b | 1.41 | 0.022 | cfa-miR-26b | 2.83 | 0.0022 |
| cfa-miR-10a | 4.05 | 0.0021 | cfa-miR-30b | 1.5 | 0.0028 |
| cfa-miR-128 | 2.03 | 0.0227 | cfa-miR-30c | 1.37 | 0.0019 |
| cfa-miR-148b | 2.3 | 0.0281 | cfa-miR-30e | 2.13 | 0.0094 |
| cfa-miR-15b | 1.19 | 0.0463 | cfa-miR-342 | 1.93 | 0.0422 |
| cfa-miR-17 | 2.9 | 0.0081 | cfa-miR-421 | 2.48 | 0.0363 |
| cfa-miR-1841 | 0.97 | 0.05 | cfa-miR-450b | 0.9 | 0.0273 |
| cfa-miR-1842 | 2.82 | 0.0154 | cfa-miR-503 | 1.37 | 0.0383 |
| cfa-miR-186 | 2.11 | 0.0036 | cfa-miR-92b | 3.14 | 0.0152 |
| cfa-miR-192 | 3.92 | 0.0017 | cfa-miR-93 | 0.73 | 0.034 |
| cfa-miR-194 | 3.96 | 0.0015 | cfa-miR-98 | 2.26 | 0.0013 |
| Human miRNAs | |||||
| hsa-let-7f-5p | 1.24 | 0.0012 | hsa-miR-1303 | −0.46 | 0.0111 |
| hsa-let-7g-3p | 0.27 | 0.0437 | hsa-miR-1306-5p | 1.6 | 0.0103 |
| hsa-let-7g-5p | 1.24 | 0.0006 | hsa-miR-1307-5p | 1.06 | 0.0086 |
| hsa-let-7i-3p | 0.75 | 0.0323 | hsa-miR-136-3p | −0.3 | 0.0274 |
| hsa-let-7i-5p | 1.55 | 0.0211 | hsa-miR-147a | 0.35 | 0.0496 |
| hsa-miR-101-3p | 1.06 | 0.0436 | hsa-miR-148b-3p | 2.3 | 0.0273 |
| hsa-miR-101-5p | 0.57 | 0.0338 | hsa-miR-152-5p | 0.37 | 0.0282 |
| hsa-miR-103a-2-5p | 1.8 | 0.0225 | hsa-miR-106a-5p | 1.47 | 0.013 |
| hsa-miR-103a-3p | 0.81 | 0.0313 | hsa-miR-15a-3p | 0.79 | 0.0354 |
| hsa-miR-211-5p | −0.3 | 0.0419 | hsa-miR-16-2-3p | 1.08 | 0.0253 |
| hsa-miR-106b-3p | 0.78 | 0.0179 | hsa-miR-17-3p | 2.9 | 0.0078 |
| hsa-miR-29b-2-5p | 2.32 | 0.0288 | hsa-miR-17-5p | 1.48 | 0.0122 |
| hsa-miR-301a-3p | 2.82 | 0.0231 | hsa-miR-186-5p | 2.11 | 0.0031 |
| hsa-miR-30b-5p | 1.5 | 0.0019 | hsa-miR-18a-3p | 2.66 | 0.0217 |
| hsa-miR-30c-5p | 1.47 | 0.0014 | hsa-miR-18a-5p | 2.32 | 0.0117 |
| hsa-miR-30d-5p | 1.07 | 0.0034 | hsa-miR-18b-5p | 2.9 | 0.0215 |
| hsa-miR-30e-3p | 2.13 | 0.0085 | hsa-miR-1908-5p | −0.53 | 0.0353 |
| hsa-miR-30e-5p | 2.86 | 0.0076 | hsa-miR-1915-3p | −0.66 | 0.0479 |
| hsa-miR-328-5p | −0.57 | 0.009 | hsa-miR-192-5p | 3.92 | 0.0017 |
| hsa-miR-339-5p | 0.86 | 0.0414 | hsa-miR-194-5p | 3.96 | 0.0014 |
| hsa-miR-33a-3p | 0.38 | 0.0439 | hsa-miR-19a-3p | 3.55 | 0.0179 |
| hsa-miR-342-3p | 1.93 | 0.0408 | hsa-miR-19b-3p | 2.04 | 0.0199 |
| hsa-miR-342-5p | 1.27 | 0.029 | hsa-miR-202-5p | 0.79 | 0.0361 |
| hsa-miR-378d | 1.53 | 0.0498 | hsa-miR-20a-5p | 1.54 | 0.0158 |
| hsa-miR-422a | 1.44 | 0.0498 | hsa-miR-20b-5p | 2 | 0.0323 |
| hsa-miR-494-3p | 2.27 | 0.0176 | hsa-miR-503-5p | 1.85 | 0.0322 |
| hsa-miR-496 | 0.34 | 0.0123 | hsa-miR-25-3p | 1.16 | 0.0277 |
| hsa-miR-502-5p | 2.04 | 0.0193 | hsa-miR-26b-5p | 2.7 | 0.0022 |
| hsa-miR-505-3p | 2 | 0.0091 | hsa-miR-509-3-5p | 0.36 | 0.0371 |
| hsa-miR-505-5p | 1 | 0.0348 | hsa-miR-509-3p | −0.27 | 0.0364 |
| hsa-miR-106b-5p | 1.41 | 0.0189 | hsa-miR-512-3p | 0.8 | 0.0481 |
| hsa-miR-107 | 0.8 | 0.033 | hsa-miR-523-3p | −0.26 | 0.0254 |
| hsa-miR-10a-5p | 4.88 | 0.0018 | hsa-miR-551b-3p | −0.29 | 0.0441 |
| hsa-miR-10b-3p | 2.18 | 0.0398 | hsa-miR-619-5p | 0.98 | 0.0287 |
| hsa-miR-1180-3p | −0.64 | 0.0376 | hsa-miR-638 | −0.68 | 0.0248 |
| hsa-miR-1207-5p | −0.62 | 0.0085 | hsa-miR-758-5p | −0.41 | 0.0305 |
| hsa-miR-1225-3p | −0.42 | 0.0491 | hsa-miR-769-5p | 1.43 | 0.0365 |
| hsa-miR-1227-5p | −0.69 | 0.0324 | hsa-miR-888-5p | -0.24 | 0.0362 |
| hsa-miR-1228-3p | 0.9 | 0.0073 | hsa-miR-891a-3p | 0.42 | 0.0164 |
| hsa-miR-1228-5p | −0.86 | 0.0282 | hsa-miR-891b | 0.33 | 0.045 |
| hsa-miR-1233-5p | −0.44 | 0.032 | hsa-miR-92b-3p | 3.14 | 0.015 |
| hsa-miR-1246 | 2.55 | 0.0476 | hsa-miR-93-3p | 1.26 | 0.0269 |
| hsa-miR-1272 | 1 | 0.0065 | hsa-miR-93-5p | 0.73 | 0.0199 |
| hsa-miR-128-3p | 2.03 | 0.0215 | hsa-miR-940 | 0.92 | 0.0472 |
| hsa-miR-1285-5p | −0.23 | 0.0477 | hsa-miR-98-5p | 2.26 | 0.0011 |
| hsa-miR-1287-3p | 0.49 | 0.0127 | hsa-miR-99b-3p | 0.44 | 0.0315 |
logFC, log fold change.
Bold names are common microRNAs found differentially expressed for both canine and human.