Figure 2. Endpoint: Infarct size (IS; % of left ventricle [LV]. Grouped by: Animal model. Result: Favors MSC treatment.
Mean effect ± standard deviation (SD) of mesenchymal stem cell (Treatment) or placebo/no treatment (Control) on the reduction of IS (% of LV) for acute myocardial infarction (AMI) mouse, rat, and swine studies and chronic ischemic cardiomyopathy (ICM) swine studies. Number of animals in each arm of the study (Total). Relative weight of each study (Weight). Mean difference between Treatment and Control with a 95% confidence interval (95% CI), using inverse variance (IV) and random effects model (Random).