Table 1.
Comparison of WSU and MSK cohorts.
| Total cases =131 | WSU 66 (50.3%) |
MSK 65 (49.6%) |
P value |
|---|---|---|---|
| Median age in years (range) | 61 (27–90) | 62 (33–90) | .92 |
| FIGO Stage | |||
| I | 39(59) | 46(70) | .31 |
| II | 6(9) | 3(5) | |
| III | 15(23) | 14(22) | |
| IV | 6(9) | 2(3) | |
| Reclassification status | |||
| Not reclassified | 41(62) | 54(83) | .01 |
| Reclassified histology subtype | 25(38) | 11(17) | |
| Undifferentiated carcinoma | 2 (8) | 5 (46) | .02 |
| Mixed endometrioid & serous carcinoma | 12 (48) | 4 (36) | >.99 |
| Mixed endometrioid & clear cell carcinoma | 0 (0) | 1 (9) | |
| FIGO 2 endometrioid with focal marked nuclear atypia | 7 (28) | 0 (0) | .03 |
| Serous carcinoma | 4(16) | 1 (9) | >.99 |
| Tumor size in cm (range)* | 5 (1–14) | 3 (0.3–11) | <. 001 |
| Myometrial invasion | |||
| Absent | 4 (6) | 8 (12) | .14 |
| Inner half | 27 (41) | 33 (51) | |
| Outer half | 35(53) | 24 (37) | |
| Lymphovascular invasion | |||
| Absent | 21 (32) | 28 (43) | .21 |
| Present | 45 (68) | 37 (57) | |
| Cervical stromal invasion | |||
| Absent | 49 (74) | 56 (86) | .12 |
| Present | 17 (26) | 9 (14) | |
| Adnexal involvement | |||
| Absent | 56 (85) | 63 (97) | .03 |
| Present | 10 (15) | 2 (3) | |
| Lymph node sampled | |||
| No | 11 (17) | 4 (6) | .10 |
| Yes | 55(83) | 61 (94) | |
| Lymph node involved** | |||
| No | 41(75) | 47(77) | .80 |
| Yes | 14(25) | 14(23) | |
| Omentum sampled | |||
| No | 33(50) | 48(74) | .01 |
| Yes | 33(50) | 17(26) | |
| Omentum involved** | |||
| No | 29(88) | 16(94) | .70 |
| Yes | 4(12) | 1(6) | |
| Adjuvant Therapy | |||
| None | 13 (20) | 7 (11) | .22 |
| Chemotherapy | 15 (22) | 8 (12) | .17 |
| Radiation | 26(40) | 40 (62) | .02 |
| Chemoradiation | 12(18) | 10 (15) | .82 |
| Recurrence | |||
| No | 50 (76) | 57 (88) | .11 |
| Yes | 16 (24) | 8 (12) |
Number in parentheses represents % except for median age and tumor size
*
missing data in 2 cases, information not available
**
subset of cases where sampling was performed
Wayne State University Pathology department in Detroit, MI (WSU)
Memorial Sloan Kettering Cancer Center, New York, NY (MSK)