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. 2017 Oct 19;11:1883–1889. doi: 10.2147/OPTH.S144369

Table 5.

Tear film break-up time

Visit 1
Predose 5 minutes 20 minutes 60 minutes
Rohto Dry-Aid 2.44 3.32 3.84 3.27
p-value vs baseline 0.011 0.006 0.012
Systane Ultra 2.27 3.09 2.87 2.75
p-value vs baseline 0.018 0.206 0.442

Notes: Mean break-up time, in seconds, scored for the worst eye only; p-values vs baseline. Mean values were significantly increased for both groups at 5 minutes, but the mean scores of the Rohto group only maintained the increased break-up time at 20 and 60 minutes. p-values in bold indicate significance (p<0.05).