Table 3.

Platelet normalization assessed using VerifyNow® (P2Y₁₂ Reaction Units - PRU)

	LOADING DOSE	MAINTENANCE THERAPY
	Aggregation (PRU) (mean ± SD)	Aggregation (PRU) (mean ± SD)
Baseline	284.1 ± 42.2	284.1 ± 42.2
Post-dose
4 hours 0%	39.1 ± 25.9	37.5 ± 32.4
25%	69.6 ± 35.6 *	72.2 ± 38.5 *
50%	100.3 ± 49.6 *	88.4 ± 42.9 *
75%	98.6 ± 54.4 *	85.9 ± 49.4 *
6 hours 0%	25.9 ± 28.9	24.0 ± 30.3
25%	55.3 ± 50.2 *	46.0 ± 37.3 *
50%	67.8 ± 53.8 *	55.4 ± 41.8 *
75%	71.2 ± 42.8 *	67.7 ± 45.3 *
24 hours 0%	127.6 ± 58.8	119.0 ± 78.0
25%	157.3 ± 52.5 *	147.6 ± 65.2 *
50%	165.9 ± 40.5 *	158.0 ± 43.5 *
75%	162.5 ± 29.4 *	154.0 ± 51.0
48 hours 0%	250.6 ± 45.8	214.8 ± 74.0
25%	249.5 ± 35.1	219.7 ± 52.2
50%	226.2 ± 51.6	221.2 ± 44.2
75%	204.2 ± 45.9	203.9 ± 41.5

^*p<0.05 vs. corresponding 0%,

^†p is not significant vs. Baseline