Skip to main content
. 2017 Sep 8;6:e24502. doi: 10.7554/eLife.24502

Figure 1. Protein kinase inhibition by ID-8.

(A) ID-8 structure. (B) top kinase targets of ID-8 by degree of inhibition at 10 μm, and inhibition of other CMGC group members. (C) kinome tree illustrating the extent of protein kinase inhibition in six families of protein kinases. Illustration reproduced courtesy of Cell Signalling Technology, Inc. (www.cellsignal.com). (D) Structures of indole compounds related to ID-8.

Figure 1.

Figure 1—figure supplement 1. Schematic illustration of chemical syntheses of ID-8 analogues.

Figure 1—figure supplement 1.