Table 5.

Level and quality of evidence of included studies n (%)

		Total Studies	Procedure groups
			MACT	BMDCT	AMIC	Cartilage ECM	ACIC	Cell-free scaffold
Level of evidence
	1	0	0	0	0	0	0	0
	2	1 (3.6)	0	2 (22.2)	0	0	0	0
	3	3 (10.7)	2 (15.4)	2 (22.2)	0	0	0	0
	4	24 (85.7)	11 (84.6)	5 (55.6)	4 (100)	2 (100)	1 (100)	1 (100)
Quality of evidence
	Excellent (MCMS ≥ 85)	0	0	0	0	0	0	0
	Good (MCMS 70-84)	0	0	0	0	0	0	0
	Fair (MCMS 55-69)	7 (25.0)	3 (23.1)	4 (44.4)	0	0	0	0
	Poor (MCMS < 55)	21 (75.0)	10 (76.9)	5 (55.6)	4 (100)	2 (100)	1 (100)	1 (100)