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Seizures, Racine Scale – Maximum severity of disease.a
| Strain | Treatment | Number of mice | Number (%) of mice with maximum clinical stages | ||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| 1 | 2 | 3 | 4 | 5 | |||
| C57BL/6J | PBS | 8 | 0 | 0 | 0 | 0 | 8 (100) |
| rIL-6 | 10 | 0 | 0 | 0 | 3 (30) | 7 (70) | |
| IL-6KO | PBS | 7 | 0 | 0 | 0 | 0 | 7 (100) |
| rIL-6 | 11 | 0 | 0 | 0 | 1 (9.1) | 10 (90.9) | |
IL-6KO, Interleukin-6 knockout; PBS, phosphate-buffered saline; rIL-6, recombinant IL-6
C57BL/6J mice infected with 3 × 105 pfu of TMEV-DA
